From Vishakapatnam(Vizag)

Air
Direct flights to Tirupati are available from Hyderabad and Chennai only.

Rail
No Direct trains are there from vishakapatnamto Kanipakam they have to reach either Tirupati or Chittoor and from there they can reach kanipakam by Bus

Train Number	Name	Vizag Dep. & Frequency	Tirupati Arr.	Tirupati Dep.& Frequency	Vizag Arr.	Fare: INR(Class)
7479/ 7480	Howrah Express	2315 (Daily)	1600	0945 (Daily)	0440	1252(2A) 796(3A) 293(SL)
7488/ 7487	Tirumala Express	1410 (Daily)	0500	1930 (Daily)	1030	1252(2A) 796(3A) 293(SL)

(Key: 1A=First Class A/C; 2A=2-tier A/C Sleeper; 3A=3-tier A/C Sleeper;
CC=A/C Chair Car; FC=First Class; SL= Sleeper Class; II=Second Class Seat)

Note: The train timings and fares are updated regularly on this site. However, please do cross-check with the Railways.

You can also use the Rail cum Road facility.

Road
Chittoor is 800Kms from Vizag.

APSRTC runs daily buses between Hyderabad and Chittoor. The types of buses are: Express/ Luxury/ Hi-tech/ AC Sleeper Coach.

The AC Sleeper Coach is comfortable as the bus is fitted with Air Suspension for effective shock absorption. Magazines and bedding are provided free of cost. Snacks, soft drinks and mineral water are provided against payment.  There is an attendant to serve passengers. The fare is INR 540per Head.